MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways.

Patel, A

MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. [electronic resource] - Oncogene May 2015 - 2586-96 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-5594

10.1038/onc.2014.195 doi


Animals
Carcinoma, Non-Small-Cell Lung--genetics
Cell Proliferation--genetics
DNA Damage
DNA Repair Enzymes--biosynthesis
Female
Gene Expression Regulation, Neoplastic
Humans
Lung Neoplasms--genetics
Male
Mice
Mice, Nude
Phosphoric Monoester Hydrolases--biosynthesis
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins p21(ras)
Tumor Suppressor Protein p53--genetics
Up-Regulation
ras Proteins--genetics