Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data.

Cheng, Donavan T

Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data. [electronic resource] - The Journal of molecular diagnostics : JMD Sep 2014 - 504-518 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1943-7811

10.1016/j.jmoldx.2014.05.006 doi


Bone Marrow Cells--metabolism
DNA Mutational Analysis--methods
Exons
Genetic Testing--methods
High-Throughput Nucleotide Sequencing--methods
Humans
Leukemia, Myeloid--diagnosis
Mutation
Myeloproliferative Disorders--diagnosis
Nucleophosmin
Polymerase Chain Reaction--methods
Polymorphism, Single Nucleotide
ROC Curve
Reproducibility of Results
Sensitivity and Specificity