Initial biological qualification of SBDP-145 as a biomarker of compound-induced neurodegeneration in the rat.

Pritt, Michael L

Initial biological qualification of SBDP-145 as a biomarker of compound-induced neurodegeneration in the rat. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology Oct 2014 - 398-408 p. digital

Publication Type: Journal Article

1096-0929

10.1093/toxsci/kfu136 doi


Animals
Biomarkers--cerebrospinal fluid
Brain--drug effects
Dose-Response Relationship, Drug
Enzyme-Linked Immunosorbent Assay
Nerve Degeneration--cerebrospinal fluid
Neurotoxicity Syndromes--cerebrospinal fluid
Peptide Fragments--cerebrospinal fluid
Predictive Value of Tests
Rats, Sprague-Dawley
Risk Assessment
Severity of Illness Index
Spectrin--cerebrospinal fluid
Time Factors
Toxicity Tests--methods