CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses.

Yamamoto, Makoto

CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses. [electronic resource] - The Journal of clinical investigation Aug 2014 - 3479-88 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1558-8238

10.1172/JCI73805 doi


Acyclovir--pharmacology
Adenoviruses, Human--drug effects
Animals
Antiviral Agents--chemistry
Cyclin-Dependent Kinase 9--antagonists & inhibitors
Cytomegalovirus--drug effects
DNA Viruses--drug effects
Disease Models, Animal
Drug Resistance, Viral
Flavonoids--pharmacology
HEK293 Cells
HeLa Cells
Herpes Simplex--drug therapy
Herpesvirus 1, Human--drug effects
Herpesvirus 2, Human--drug effects
Host-Pathogen Interactions--drug effects
Humans
Mice
Mice, Inbred ICR
Piperidines--pharmacology
Protein Kinase Inhibitors--chemistry
Pyridines--chemistry
Rats
Rats, Wistar
Transcription, Genetic--drug effects
Transcriptome--drug effects
Virus Replication--drug effects