The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice.
Peters, Marco
The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice. [electronic resource] - Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Dec 2014 - 2938-48 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1740-634X
10.1038/npp.2014.154 doi
Age Factors
Aging--drug effects
Animals
Brain-Derived Neurotrophic Factor--metabolism
CREB-Binding Protein--metabolism
Cells, Cultured
Conditioning, Psychological--drug effects
Early Growth Response Protein 1--metabolism
Embryo, Mammalian
Exploratory Behavior--drug effects
Fear--psychology
Gene Expression Regulation--drug effects
Hippocampus--physiology
Male
Maze Learning--drug effects
Memory, Long-Term--drug effects
Mice
Neurons--drug effects
Phosphodiesterase 4 Inhibitors--pharmacology
Piperidones--pharmacology
Protein Binding--drug effects
Proto-Oncogene Proteins c-fos--metabolism
Rolipram--pharmacology
The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice. [electronic resource] - Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Dec 2014 - 2938-48 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1740-634X
10.1038/npp.2014.154 doi
Age Factors
Aging--drug effects
Animals
Brain-Derived Neurotrophic Factor--metabolism
CREB-Binding Protein--metabolism
Cells, Cultured
Conditioning, Psychological--drug effects
Early Growth Response Protein 1--metabolism
Embryo, Mammalian
Exploratory Behavior--drug effects
Fear--psychology
Gene Expression Regulation--drug effects
Hippocampus--physiology
Male
Maze Learning--drug effects
Memory, Long-Term--drug effects
Mice
Neurons--drug effects
Phosphodiesterase 4 Inhibitors--pharmacology
Piperidones--pharmacology
Protein Binding--drug effects
Proto-Oncogene Proteins c-fos--metabolism
Rolipram--pharmacology