RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

Maatz, Henrike

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing. [electronic resource] - The Journal of clinical investigation Aug 2014 - 3419-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1558-8238

10.1172/JCI74523 doi


Alternative Splicing
Animals
Base Sequence
Binding Sites--genetics
Cardiomyopathy, Dilated--complications
Cohort Studies
Exons
Heart Failure--etiology
Humans
Mutation
Myocardium--metabolism
Myocytes, Cardiac--metabolism
RNA Precursors--genetics
RNA Processing, Post-Transcriptional
RNA Splice Sites
RNA-Binding Proteins--genetics
Rats
Rats, Sprague-Dawley
Ribonucleoprotein, U1 Small Nuclear--metabolism
Ribonucleoprotein, U2 Small Nuclear--metabolism
Selection, Genetic
Spliceosomes--metabolism