ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment.

Fang, Ling

ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment. [electronic resource] - Nucleic acids research Jul 2014 - 8416-32 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1362-4962

10.1093/nar/gku529 doi


Ataxia Telangiectasia Mutated Proteins--metabolism
Cell Line
Cell Nucleus--metabolism
Cyclic AMP-Dependent Protein Kinase Catalytic Subunits--metabolism
Cyclin-Dependent Kinase 9--genetics
Cytokines--genetics
Gene Expression Regulation
Genes, Immediate-Early
Humans
I-kappa B Kinase--metabolism
I-kappa B Proteins--metabolism
NF-KappaB Inhibitor alpha
NF-kappa B--metabolism
Phosphorylation
Promoter Regions, Genetic
Serine--metabolism
Transcription Factor RelA--chemistry
Tumor Necrosis Factor-alpha--pharmacology
Ubiquitination
beta-Transducin Repeat-Containing Proteins--metabolism