Local and systemic tolerability of a 2'O-methoxyethyl antisense oligonucleotide targeting interleukin-4 receptor-α delivery by inhalation in mouse and monkey.

Fey, Robert A

Local and systemic tolerability of a 2'O-methoxyethyl antisense oligonucleotide targeting interleukin-4 receptor-α delivery by inhalation in mouse and monkey. [electronic resource] - Inhalation toxicology Jul 2014 - 452-63 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1091-7691

10.3109/08958378.2014.907587 doi


Animals
Female
Lung--drug effects
Macaca
Male
Mice
Oligonucleotides--blood
Oligonucleotides, Antisense--blood
RNA, Messenger--metabolism
Receptors, Cell Surface--genetics