Construction and evaluation of a novel humanized HER2-specific chimeric receptor.
Sun, Meili
Construction and evaluation of a novel humanized HER2-specific chimeric receptor. [electronic resource] - Breast cancer research : BCR Jun 2014 - R61 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1465-542X
10.1186/bcr3674 doi
Animals
Antibodies, Monoclonal--genetics
Antibodies, Monoclonal, Humanized--pharmacology
Antineoplastic Agents
Breast Neoplasms--drug therapy
CD28 Antigens--genetics
CD3 Complex--genetics
Cell Line, Tumor
Chromium Isotopes--chemistry
Drug Resistance, Neoplasm
Female
Gene Transfer Techniques
Humans
Interferon-gamma--immunology
Interleukin-2--immunology
MCF-7 Cells
Mice
Mice, Inbred NOD
Mice, SCID
Neoplasm Transplantation
Ovarian Neoplasms--drug therapy
Receptor, ErbB-2--antagonists & inhibitors
Recombinant Fusion Proteins--genetics
Single-Chain Antibodies--genetics
T-Lymphocytes--immunology
Transplantation, Heterologous
Trastuzumab
Construction and evaluation of a novel humanized HER2-specific chimeric receptor. [electronic resource] - Breast cancer research : BCR Jun 2014 - R61 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1465-542X
10.1186/bcr3674 doi
Animals
Antibodies, Monoclonal--genetics
Antibodies, Monoclonal, Humanized--pharmacology
Antineoplastic Agents
Breast Neoplasms--drug therapy
CD28 Antigens--genetics
CD3 Complex--genetics
Cell Line, Tumor
Chromium Isotopes--chemistry
Drug Resistance, Neoplasm
Female
Gene Transfer Techniques
Humans
Interferon-gamma--immunology
Interleukin-2--immunology
MCF-7 Cells
Mice
Mice, Inbred NOD
Mice, SCID
Neoplasm Transplantation
Ovarian Neoplasms--drug therapy
Receptor, ErbB-2--antagonists & inhibitors
Recombinant Fusion Proteins--genetics
Single-Chain Antibodies--genetics
T-Lymphocytes--immunology
Transplantation, Heterologous
Trastuzumab