Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety.

Chiu, Gabriel S

Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety. [electronic resource] - Brain, behavior, and immunity Oct 2014 - 218-31 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1090-2139

10.1016/j.bbi.2014.05.018 doi


Adenosine--pharmacology
Amygdala--metabolism
Animals
Anxiety--chemically induced
Brain--metabolism
Carbazoles--pharmacology
Caspase 1--deficiency
Cyclic AMP-Dependent Protein Kinases--physiology
Enzyme Activation--drug effects
Exploratory Behavior--drug effects
Feeding Behavior--drug effects
Glyburide--pharmacology
Interleukin-1beta--biosynthesis
Ion Transport--drug effects
KATP Channels--physiology
Locomotion--drug effects
Maze Learning--drug effects
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
Nerve Tissue Proteins--deficiency
Potassium--metabolism
Pyrroles--pharmacology
Receptor, Adenosine A2A--deficiency
Receptors, Interleukin-1 Type I--deficiency