In vitro and in vivo anticancer activity of copper(I) complexes with homoscorpionate tridentate tris(pyrazolyl)borate and auxiliary monodentate phosphine ligands.
Gandin, Valentina
In vitro and in vivo anticancer activity of copper(I) complexes with homoscorpionate tridentate tris(pyrazolyl)borate and auxiliary monodentate phosphine ligands. [electronic resource] - Journal of medicinal chemistry Jun 2014 - 4745-60 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm500279x doi
Animals
Antineoplastic Agents--chemical synthesis
Azoles--chemistry
Borates--chemistry
Carcinoma, Lewis Lung--drug therapy
Cell Death--drug effects
Cell Line, Tumor
Chelating Agents--chemistry
Coordination Complexes--chemical synthesis
Copper
Crystallography, X-Ray
Drug Screening Assays, Antitumor
Endoplasmic Reticulum Stress
Mice
Phosphines--chemistry
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors--chemical synthesis
Structure-Activity Relationship
Unfolded Protein Response
In vitro and in vivo anticancer activity of copper(I) complexes with homoscorpionate tridentate tris(pyrazolyl)borate and auxiliary monodentate phosphine ligands. [electronic resource] - Journal of medicinal chemistry Jun 2014 - 4745-60 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm500279x doi
Animals
Antineoplastic Agents--chemical synthesis
Azoles--chemistry
Borates--chemistry
Carcinoma, Lewis Lung--drug therapy
Cell Death--drug effects
Cell Line, Tumor
Chelating Agents--chemistry
Coordination Complexes--chemical synthesis
Copper
Crystallography, X-Ray
Drug Screening Assays, Antitumor
Endoplasmic Reticulum Stress
Mice
Phosphines--chemistry
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors--chemical synthesis
Structure-Activity Relationship
Unfolded Protein Response