Induction of p21CIP1 protein and cell cycle arrest after inhibition of Aurora B kinase is attributed to aneuploidy and reactive oxygen species.

Kumari, Geeta

Induction of p21CIP1 protein and cell cycle arrest after inhibition of Aurora B kinase is attributed to aneuploidy and reactive oxygen species. [electronic resource] - The Journal of biological chemistry Jun 2014 - 16072-84 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M114.555060 doi


Aneuploidy
Aurora Kinase B--drug effects
Cell Cycle
Cell Line
Cyclin-Dependent Kinase Inhibitor p21--biosynthesis
Flow Cytometry
Humans
In Situ Hybridization, Fluorescence
Protein Kinase Inhibitors--pharmacology
Reactive Oxygen Species--metabolism
Signal Transduction
p38 Mitogen-Activated Protein Kinases--metabolism