PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
Eren, Mesut
PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America May 2014 - 7090-5 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1091-6490
10.1073/pnas.1321942111 doi
Aging--physiology
Animals
Cellular Senescence--physiology
Cyclin-Dependent Kinase Inhibitor p16--genetics
Extracellular Space--metabolism
Female
Fibroblast Growth Factor-23
Glucuronidase--genetics
Hemorrhagic Disorders--genetics
Klotho Proteins
Longevity--physiology
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Knockout
Phenotype
Plasminogen Activator Inhibitor 1--deficiency
Proteolysis
Serpin E2--genetics
Telomere--physiology
PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America May 2014 - 7090-5 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1091-6490
10.1073/pnas.1321942111 doi
Aging--physiology
Animals
Cellular Senescence--physiology
Cyclin-Dependent Kinase Inhibitor p16--genetics
Extracellular Space--metabolism
Female
Fibroblast Growth Factor-23
Glucuronidase--genetics
Hemorrhagic Disorders--genetics
Klotho Proteins
Longevity--physiology
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Knockout
Phenotype
Plasminogen Activator Inhibitor 1--deficiency
Proteolysis
Serpin E2--genetics
Telomere--physiology