Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis.

Cazanave, S C

Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis. [electronic resource] - Cell death and differentiation Aug 2014 - 1303-12 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-5403

10.1038/cdd.2014.49 doi


Adaptor Proteins, Signal Transducing--genetics
Animals
Apoptosis--physiology
Apoptosis Regulatory Proteins--genetics
Bcl-2-Like Protein 11
Cell Line, Tumor
Cytoskeletal Proteins--genetics
HEK293 Cells
Hep G2 Cells
Hepatocytes--metabolism
Humans
Intracellular Signaling Peptides and Proteins--genetics
Kelch-Like ECH-Associated Protein 1
Membrane Proteins--genetics
Mice
Mice, Inbred C57BL
Mice, Knockout
Phosphorylation
Proto-Oncogene Proteins--genetics
Tumor Suppressor Proteins--genetics