Sustained exposure to the investigational Kisspeptin analog, TAK-448, down-regulates testosterone into the castration range in healthy males and in patients with prostate cancer: results from two phase 1 studies.
MacLean, David B
Sustained exposure to the investigational Kisspeptin analog, TAK-448, down-regulates testosterone into the castration range in healthy males and in patients with prostate cancer: results from two phase 1 studies. [electronic resource] - The Journal of clinical endocrinology and metabolism Aug 2014 - E1445-53 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
1945-7197
10.1210/jc.2013-4236 doi
Adult
Aged
Dose-Response Relationship, Drug
Down-Regulation--drug effects
Drug Administration Schedule
Drugs, Investigational--administration & dosage
Health
Humans
Kisspeptins--administration & dosage
Luteinizing Hormone--blood
Male
Middle Aged
Orchiectomy
Placebos
Prostatic Neoplasms--blood
Testosterone--blood
Sustained exposure to the investigational Kisspeptin analog, TAK-448, down-regulates testosterone into the castration range in healthy males and in patients with prostate cancer: results from two phase 1 studies. [electronic resource] - The Journal of clinical endocrinology and metabolism Aug 2014 - E1445-53 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
1945-7197
10.1210/jc.2013-4236 doi
Adult
Aged
Dose-Response Relationship, Drug
Down-Regulation--drug effects
Drug Administration Schedule
Drugs, Investigational--administration & dosage
Health
Humans
Kisspeptins--administration & dosage
Luteinizing Hormone--blood
Male
Middle Aged
Orchiectomy
Placebos
Prostatic Neoplasms--blood
Testosterone--blood