IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice.

Jackaman, C

IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice. [electronic resource] - Age (Dordrecht, Netherlands) Jun 2014 - 9655 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1574-4647

10.1007/s11357-014-9655-y doi


Aging--immunology
Animals
CD40 Antigens--pharmacology
Cell Line, Tumor
Cell Proliferation
Flow Cytometry
Immunity, Innate
Immunotherapy--methods
Interleukin-2--pharmacology
Lung Neoplasms--drug therapy
Macrophages, Peritoneal--metabolism
Mesothelioma--drug therapy
Mesothelioma, Malignant
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Neoplasms, Experimental
T-Lymphocytes--metabolism