The tricyclic antidepressant desipramine inhibited the neurotoxic, kainate-induced [Ca(2+)]i increases in CA1 pyramidal cells in acute hippocampal slices.

Koncz, István

The tricyclic antidepressant desipramine inhibited the neurotoxic, kainate-induced [Ca(2+)]i increases in CA1 pyramidal cells in acute hippocampal slices. [electronic resource] - Brain research bulletin May 2014 - 42-51 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-2747

10.1016/j.brainresbull.2014.04.003 doi


Animals
Antidepressive Agents, Tricyclic--pharmacology
CA1 Region, Hippocampal--drug effects
Calcium--metabolism
Desipramine--pharmacology
Excitatory Amino Acid Agonists--toxicity
Kainic Acid--toxicity
Pyramidal Cells--drug effects
Rats
Rats, Wistar