Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice.
Tong, Hua Hua
Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice. [electronic resource] - PloS one 2014 - e95160 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1932-6203
10.1371/journal.pone.0095160 doi
Acute Disease
Animals
Coinfection
Complement Activation
Complement C1q--deficiency
Complement C3a--genetics
Complement C5a--genetics
Complement Factor B--deficiency
Eustachian Tube--immunology
Female
Gene Deletion
Gene Expression
Immunity, Innate
Influenza A Virus, H1N1 Subtype--immunology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Orthomyxoviridae Infections--genetics
Otitis Media--genetics
Pneumococcal Infections--genetics
Receptor, Anaphylatoxin C5a--deficiency
Severity of Illness Index
Streptococcus pneumoniae--immunology
Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice. [electronic resource] - PloS one 2014 - e95160 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1932-6203
10.1371/journal.pone.0095160 doi
Acute Disease
Animals
Coinfection
Complement Activation
Complement C1q--deficiency
Complement C3a--genetics
Complement C5a--genetics
Complement Factor B--deficiency
Eustachian Tube--immunology
Female
Gene Deletion
Gene Expression
Immunity, Innate
Influenza A Virus, H1N1 Subtype--immunology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Orthomyxoviridae Infections--genetics
Otitis Media--genetics
Pneumococcal Infections--genetics
Receptor, Anaphylatoxin C5a--deficiency
Severity of Illness Index
Streptococcus pneumoniae--immunology