TPMT and MTHFR genotype is not associated with altered risk of thioguanine-related sinusoidal obstruction syndrome in pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group.

Wray, Lisa

TPMT and MTHFR genotype is not associated with altered risk of thioguanine-related sinusoidal obstruction syndrome in pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group. [electronic resource] - Pediatric blood & cancer Nov 2014 - 2086-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1545-5017

10.1002/pbc.25057 doi


Antimetabolites, Antineoplastic--adverse effects
Child
Child, Preschool
Female
Genotype
Hepatic Veno-Occlusive Disease--chemically induced
Humans
Infant
Male
Methylenetetrahydrofolate Reductase (NADPH2)--genetics
Methyltransferases--genetics
Polymorphism, Single Nucleotide
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Thioguanine--adverse effects