MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL.

van der Linden, Marieke H

MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL. [electronic resource] - Cell cycle (Georgetown, Tex.) 2014 - 834-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1551-4005

10.4161/cc.27757 doi


Antineoplastic Agents--pharmacology
Cell Fusion
Cell Line, Tumor
Cell Proliferation
Cyclin-Dependent Kinase 6--genetics
Enhancer of Zeste Homolog 2 Protein
G1 Phase--drug effects
Humans
Infant
Myeloid-Lymphoid Leukemia Protein--genetics
Oncogene Proteins, Fusion--genetics
Piperazines--pharmacology
Polycomb Repressive Complex 2--genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma--metabolism
Pyridines--pharmacology
Salivary Proline-Rich Proteins--genetics