Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence.
Dhanya, Raveendra-Panickar
Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence. [electronic resource] - Journal of medicinal chemistry May 2014 - 4154-72 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm5000563 doi
Allosteric Regulation
Animals
Cocaine-Related Disorders--drug therapy
Disease Models, Animal
Dose-Response Relationship, Drug
Drug Design
HEK293 Cells
Humans
Male
Rats
Rats, Wistar
Receptors, Metabotropic Glutamate--agonists
Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence. [electronic resource] - Journal of medicinal chemistry May 2014 - 4154-72 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm5000563 doi
Allosteric Regulation
Animals
Cocaine-Related Disorders--drug therapy
Disease Models, Animal
Dose-Response Relationship, Drug
Drug Design
HEK293 Cells
Humans
Male
Rats
Rats, Wistar
Receptors, Metabotropic Glutamate--agonists