Inhibiting Na+/K+ ATPase can impair mitochondrial energetics and induce abnormal Ca2+ cycling and automaticity in guinea pig cardiomyocytes.

Li, Qince

Inhibiting Na+/K+ ATPase can impair mitochondrial energetics and induce abnormal Ca2+ cycling and automaticity in guinea pig cardiomyocytes. [electronic resource] - PloS one 2014 - e93928 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0093928 doi


Action Potentials
Adenosine Triphosphate--metabolism
Animals
Antioxidants--metabolism
Arrhythmias, Cardiac--metabolism
Calcium--metabolism
Computer Simulation
Guinea Pigs
Homeostasis
Ions
Membrane Potentials
Mitochondria--enzymology
Myocytes, Cardiac--cytology
Oxidative Phosphorylation
Reactive Oxygen Species--metabolism
Sodium-Potassium-Exchanging ATPase--metabolism