Targeting mTOR dependency in pancreatic cancer.

Morran, Douglas C

Targeting mTOR dependency in pancreatic cancer. [electronic resource] - Gut Sep 2014 - 1481-9 p. digital

Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't

1468-3288

10.1136/gutjnl-2013-306202 doi


Animals
Antineoplastic Agents--therapeutic use
Biomarkers, Tumor--antagonists & inhibitors
Carcinoma, Pancreatic Ductal--diagnostic imaging
Cell Line, Tumor
Drug Administration Schedule
Gene Expression Regulation, Neoplastic
Humans
Injections, Intraperitoneal
Mice
Mice, Mutant Strains
Mutation
PTEN Phosphohydrolase--deficiency
Pancreatic Neoplasms--diagnostic imaging
Positron-Emission Tomography
Protein Kinase Inhibitors--therapeutic use
Proto-Oncogene Proteins p21(ras)--deficiency
Sirolimus--therapeutic use
TOR Serine-Threonine Kinases--antagonists & inhibitors
Treatment Outcome
Tumor Suppressor Protein p53--deficiency