Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors.

Nader, Joëlle

Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors. [electronic resource] - Neuropharmacology Dec 2014 - 214-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-7064

10.1016/j.neuropharm.2014.03.014 doi


Animals
Arachidonic Acids--metabolism
Benzamides--pharmacology
Benzodioxoles--pharmacology
Cannabinoid Receptor Modulators--pharmacology
Carbamates--pharmacology
Central Nervous System Stimulants--toxicity
Dronabinol--pharmacology
Endocannabinoids--metabolism
Enzyme Inhibitors--pharmacology
Glycerides--metabolism
Male
Methamphetamine--toxicity
Mice, Inbred C57BL
Neostriatum--drug effects
Neurotoxicity Syndromes--metabolism
Piperidines--pharmacology
Polyunsaturated Alkamides--metabolism
Random Allocation
Receptor, Cannabinoid, CB1--agonists
Receptor, Cannabinoid, CB2--agonists
Tumor Necrosis Factor-alpha--metabolism
Tyrosine 3-Monooxygenase--metabolism