Development, characterization and application of in situ gel systems for intranasal delivery of tacrine.

Qian, Shuai

Development, characterization and application of in situ gel systems for intranasal delivery of tacrine. [electronic resource] - International journal of pharmaceutics Jul 2014 - 272-82 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1873-3476

10.1016/j.ijpharm.2014.04.015 doi


Administration, Intranasal
Administration, Oral
Animals
Area Under Curve
Biological Availability
Chemistry, Pharmaceutical
Chitosan--chemistry
Cholinesterase Inhibitors--administration & dosage
Drug Carriers
Gels
Male
Mucociliary Clearance
Nasal Cavity--metabolism
Phase Transition
Poloxamer--chemistry
Polyethylene Glycols--chemistry
Rats, Sprague-Dawley
Rheology
Solubility
Tacrine--administration & dosage
Technology, Pharmaceutical--methods
Transition Temperature