Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress.

Gonzalez, Yanira

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress. [electronic resource] - Oncotarget Mar 2014 - 1526-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1949-2553

10.18632/oncotarget.1715 doi


Animals
Apoptosis--drug effects
Apoptosis Regulatory Proteins--antagonists & inhibitors
Autophagy--drug effects
Autophagy-Related Protein 7
Beclin-1
Blotting, Western
Breast Neoplasms--drug therapy
Cell Proliferation--drug effects
Female
Humans
Immunoenzyme Techniques
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Kelch-Like ECH-Associated Protein 1
Membrane Proteins--antagonists & inhibitors
Mice
NF-E2-Related Factor 2--genetics
Organophosphorus Compounds--pharmacology
Oxidative Stress--drug effects
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Tumor Cells, Cultured
Ubiquinone--analogs & derivatives
Ubiquitin-Activating Enzymes--antagonists & inhibitors