Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma.
Fuchs, Bryan C
Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma. [electronic resource] - Hepatology (Baltimore, Md.) Apr 2014 - 1577-90 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1527-3350
10.1002/hep.26898 doi
Animals
Bile Ducts--physiopathology
Carbon Tetrachloride--adverse effects
Carcinoma, Hepatocellular--pathology
Cell Proliferation--drug effects
Cells, Cultured
Diethylnitrosamine--adverse effects
Disease Models, Animal
Disease Progression
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Hepatic Stellate Cells--drug effects
Hepatocytes--drug effects
Humans
Ligation--adverse effects
Liver Cirrhosis--etiology
Liver Neoplasms--pathology
Male
Mice
Mice, Inbred Strains
Phosphorylation--drug effects
Prognosis
Quinazolines--pharmacology
Rats
Rats, Wistar
Transcriptome
Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma. [electronic resource] - Hepatology (Baltimore, Md.) Apr 2014 - 1577-90 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1527-3350
10.1002/hep.26898 doi
Animals
Bile Ducts--physiopathology
Carbon Tetrachloride--adverse effects
Carcinoma, Hepatocellular--pathology
Cell Proliferation--drug effects
Cells, Cultured
Diethylnitrosamine--adverse effects
Disease Models, Animal
Disease Progression
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Hepatic Stellate Cells--drug effects
Hepatocytes--drug effects
Humans
Ligation--adverse effects
Liver Cirrhosis--etiology
Liver Neoplasms--pathology
Male
Mice
Mice, Inbred Strains
Phosphorylation--drug effects
Prognosis
Quinazolines--pharmacology
Rats
Rats, Wistar
Transcriptome