DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.

Pitroda, Sean P

DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy. [electronic resource] - Science translational medicine Mar 2014 - 229ra42 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1946-6242

10.1126/scitranslmed.3008291 doi


Antineoplastic Agents--pharmacology
Cell Line, Tumor
DNA Repair--drug effects
DNA Replication--drug effects
Drug Therapy
Gene Expression Regulation, Neoplastic--drug effects
Genomic Instability--drug effects
Homologous Recombination--drug effects
Humans
Neoplasms--drug therapy
Prognosis
Stress, Physiological--drug effects