Plant-derived recombinant immune complexes as self-adjuvanting TB immunogens for mucosal boosting of BCG.

Pepponi, Ilaria

Plant-derived recombinant immune complexes as self-adjuvanting TB immunogens for mucosal boosting of BCG. [electronic resource] - Plant biotechnology journal Sep 2014 - 840-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1467-7652

10.1111/pbi.12185 doi


Adjuvants, Immunologic--biosynthesis
Administration, Intranasal
Animals
Antibody Formation
Antigen-Antibody Complex--metabolism
CD4-Positive T-Lymphocytes--metabolism
Cell Proliferation
Cloning, Molecular
Humans
Interleukin-2--metabolism
Mice
Mycobacterium tuberculosis--immunology
Plants, Genetically Modified--metabolism
Nicotiana--genetics
Tuberculosis Vaccines--administration & dosage
Tumor Necrosis Factor-alpha--metabolism