Altered agonist sensitivity of a mutant v2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus.

Erdélyi, László Sándor

Altered agonist sensitivity of a mutant v2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus. [electronic resource] - Molecular endocrinology (Baltimore, Md.) May 2014 - 634-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1944-9917

10.1210/me.2013-1424 doi


Adult
Animals
Antidiuretic Agents--pharmacology
Cyclic AMP--metabolism
DNA Mutational Analysis
Deamino Arginine Vasopressin--pharmacology
Diabetes Insipidus, Nephrogenic--drug therapy
Endoplasmic Reticulum
HEK293 Cells
Humans
In Vitro Techniques
Male
Mice
Mutation, Missense
Neurophysins--pharmacology
Protein Precursors--pharmacology
Rats
Receptors, Vasopressin--agonists
Second Messenger Systems
Vasopressins--pharmacology