Plant flavone apigenin binds to nucleic acid bases and reduces oxidative DNA damage in prostate epithelial cells.

Sharma, Haripaul

Plant flavone apigenin binds to nucleic acid bases and reduces oxidative DNA damage in prostate epithelial cells. [electronic resource] - PloS one 2014 - e91588 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0091588 doi


8-Hydroxy-2'-Deoxyguanosine
Apigenin--chemistry
Cell Death--drug effects
Cell Line, Tumor
Cytoprotection--drug effects
DNA--metabolism
DNA Damage
Deoxyguanosine--analogs & derivatives
Endocytosis--drug effects
Epithelial Cells--drug effects
Humans
Hydrogen Peroxide--toxicity
Kinetics
Male
Nucleic Acids--metabolism
Oxidation-Reduction--drug effects
Prostate--cytology
Prostatic Neoplasms--pathology
Reactive Oxygen Species--metabolism
Spectrophotometry, Ultraviolet
Subcellular Fractions--drug effects