Curcumin eliminates the effect of advanced glycation end-products (AGEs) on the divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling.

Tang, Youcai

Curcumin eliminates the effect of advanced glycation end-products (AGEs) on the divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling. [electronic resource] - Laboratory investigation; a journal of technical methods and pathology May 2014 - 503-16 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1530-0307

10.1038/labinvest.2014.42 doi


Animals
Antineoplastic Agents--pharmacology
Cells, Cultured
Chromones
Curcuma
Curcumin--pharmacology
Gene Expression Regulation--drug effects
Glycation End Products, Advanced--antagonists & inhibitors
Hepatic Stellate Cells--drug effects
Leptin--antagonists & inhibitors
Liver Cirrhosis--prevention & control
Male
Mice
Mice, Inbred C57BL
Morpholines
Plant Extracts--pharmacology
Rats
Rats, Sprague-Dawley
Receptor for Advanced Glycation End Products
Receptors, Immunologic--metabolism
Receptors, Leptin--metabolism
Tyrphostins