Mutations in PIK3CD can cause hyper IgM syndrome (HIGM) associated with increased cancer susceptibility.

Crank, M C

Mutations in PIK3CD can cause hyper IgM syndrome (HIGM) associated with increased cancer susceptibility. [electronic resource] - Journal of clinical immunology Apr 2014 - 272-6 p. digital

Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Intramural

1573-2592

10.1007/s10875-014-0012-9 doi


Adult
Biopsy
Child
Class I Phosphatidylinositol 3-Kinases--genetics
Female
Genetic Predisposition to Disease
Heterozygote
Humans
Hyper-IgM Immunodeficiency Syndrome--complications
Lymph Nodes--pathology
Male
Mutation
Neoplasms--diagnosis
Pedigree
Young Adult