Highly efficient expression of interleukin-2 under the control of rabbit β-globin intron II gene enhances protective immune responses of porcine reproductive and respiratory syndrome (PRRS) DNA vaccine in pigs.
Du, Yijun
Highly efficient expression of interleukin-2 under the control of rabbit β-globin intron II gene enhances protective immune responses of porcine reproductive and respiratory syndrome (PRRS) DNA vaccine in pigs. [electronic resource] - PloS one 2014 - e90326 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0090326 doi
Animals
Antibodies, Viral--blood
Blotting, Western
Cell Proliferation
Cytokines--immunology
Female
Gene Expression--immunology
Genetic Vectors--genetics
Glycoproteins--genetics
HEK293 Cells
Humans
Immunity, Cellular--immunology
Immunity, Humoral--immunology
Interleukin-2--genetics
Introns--genetics
Lymphocytes--immunology
Mice, Inbred BALB C
Porcine Reproductive and Respiratory Syndrome--immunology
Porcine respiratory and reproductive syndrome virus--genetics
Rabbits
Reverse Transcriptase Polymerase Chain Reaction
Swine
Vaccines, DNA--administration & dosage
Viral Proteins--genetics
beta-Globins--genetics
Highly efficient expression of interleukin-2 under the control of rabbit β-globin intron II gene enhances protective immune responses of porcine reproductive and respiratory syndrome (PRRS) DNA vaccine in pigs. [electronic resource] - PloS one 2014 - e90326 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0090326 doi
Animals
Antibodies, Viral--blood
Blotting, Western
Cell Proliferation
Cytokines--immunology
Female
Gene Expression--immunology
Genetic Vectors--genetics
Glycoproteins--genetics
HEK293 Cells
Humans
Immunity, Cellular--immunology
Immunity, Humoral--immunology
Interleukin-2--genetics
Introns--genetics
Lymphocytes--immunology
Mice, Inbred BALB C
Porcine Reproductive and Respiratory Syndrome--immunology
Porcine respiratory and reproductive syndrome virus--genetics
Rabbits
Reverse Transcriptase Polymerase Chain Reaction
Swine
Vaccines, DNA--administration & dosage
Viral Proteins--genetics
beta-Globins--genetics