TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways.

Xu, Jun

TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways. [electronic resource] - Journal of leukocyte biology Jul 2014 - 93-103 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1938-3673

10.1189/jlb.2A0713-393RR doi


Animals
Autocrine Communication--genetics
Dendritic Cells--metabolism
Exodeoxyribonucleases--biosynthesis
Genetic Therapy
Genetic Vectors
HIV Infections--genetics
HIV-1--genetics
Interferon-beta--genetics
Ligands
Mice
Mice, Knockout
NF-kappa B--genetics
Phosphoproteins--biosynthesis
STAT1 Transcription Factor--genetics
STAT2 Transcription Factor--genetics
Signal Transduction
Spleen--metabolism
Toll-Like Receptors--agonists
Up-Regulation