Design, synthesis, biological evaluation, and molecular modeling of coumarin-piperazine derivatives as acetylcholinesterase inhibitors.

Modh, Rahul P

Design, synthesis, biological evaluation, and molecular modeling of coumarin-piperazine derivatives as acetylcholinesterase inhibitors. [electronic resource] - Archiv der Pharmazie Nov 2013 - 793-804 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-4184

10.1002/ardp.201300242 doi


Acetylcholinesterase--metabolism
Alzheimer Disease--drug therapy
Cholinesterase Inhibitors--chemical synthesis
Coumarins--chemical synthesis
Drug Design
GPI-Linked Proteins--antagonists & inhibitors
Humans
Hydrophobic and Hydrophilic Interactions
Molecular Docking Simulation
Piperazines--chemical synthesis
Quantitative Structure-Activity Relationship