Phosphorylation of eIF2α is dispensable for differentiation but required at a posttranscriptional level for paneth cell function and intestinal homeostasis in mice.

Cao, Stewart S

Phosphorylation of eIF2α is dispensable for differentiation but required at a posttranscriptional level for paneth cell function and intestinal homeostasis in mice. [electronic resource] - Inflammatory bowel diseases Apr 2014 - 712-22 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1536-4844

10.1097/MIB.0000000000000010 doi


Animals
Apoptosis
Cell Differentiation
Cell Proliferation
Colitis--chemically induced
Dextran Sulfate
Disease Susceptibility
Endoplasmic Reticulum--metabolism
Eukaryotic Initiation Factor-2--genetics
Homeostasis
Interferon-gamma--metabolism
Mice
Mice, Inbred C3H
Mice, Transgenic
Molecular Chaperones
Muramidase--biosynthesis
Paneth Cells--immunology
Phosphorylation
Protein Biosynthesis
RNA, Messenger--metabolism
Ribosomes--physiology
Salmonella Infections, Animal--immunology
Secretory Vesicles--ultrastructure
Signal Transduction
Stress, Physiological
Unfolded Protein Response--genetics