Neurological protection by dichloroacetate depending on the severity of injury in the paraplegic rat.

LeMay, D R

Neurological protection by dichloroacetate depending on the severity of injury in the paraplegic rat. [electronic resource] - Journal of neurosurgery Jul 1990 - 118-22 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

0022-3085

10.3171/jns.1990.73.1.0118 doi


Acetates--pharmacology
Animals
Brain Ischemia--complications
Citric Acid Cycle--drug effects
Dichloroacetic Acid--administration & dosage
Dose-Response Relationship, Drug
Glycolysis--drug effects
Hyperglycemia--complications
Iodoacetates--administration & dosage
Male
Paraplegia--etiology
Pyruvate Dehydrogenase Complex--physiology
Rats
Rats, Inbred Strains
Spinal Cord Injuries--complications