Patient-derived skeletal dysplasia induced pluripotent stem cells display abnormal chondrogenic marker expression and regulation by BMP2 and TGFβ1.

Saitta, Biagio

Patient-derived skeletal dysplasia induced pluripotent stem cells display abnormal chondrogenic marker expression and regulation by BMP2 and TGFβ1. [electronic resource] - Stem cells and development Jul 2014 - 1464-78 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1557-8534

10.1089/scd.2014.0014 doi


Base Sequence
Biomarkers--metabolism
Bone Morphogenetic Protein 2--physiology
Cell Differentiation
Cells, Cultured
Chondrogenesis
Collagen Type I--genetics
Collagen Type I, alpha 1 Chain
DNA Mutational Analysis
Dwarfism--genetics
Gene Expression
Gene Expression Regulation
Humans
Induced Pluripotent Stem Cells--metabolism
Mutation, Missense
Osteochondrodysplasias--genetics
TRPV Cation Channels--genetics
Transforming Growth Factor beta1--physiology