A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.

Okada, Nobuhiro

A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression. [electronic resource] - Genes & development Mar 2014 - 438-50 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1549-5477

10.1101/gad.233585.113 doi


Adenocarcinoma--physiopathology
Adenocarcinoma of Lung
Animals
Cell Line, Tumor
Feedback, Physiological
Gene Deletion
Gene Expression Regulation, Neoplastic
Haploinsufficiency
Humans
Lung Neoplasms--physiopathology
Mice
MicroRNAs--genetics
Proto-Oncogene Proteins--genetics
Tumor Cells, Cultured
Tumor Suppressor Protein p53--genetics
ras Proteins--genetics