Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain.

Bashtrykov, Pavel

Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain. [electronic resource] - Chembiochem : a European journal of chemical biology Mar 2014 - 743-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1439-7633

10.1002/cbic.201300740 doi


Catalytic Domain
Cell Line, Tumor
DNA (Cytosine-5-)-Methyltransferase 1
DNA (Cytosine-5-)-Methyltransferases--chemistry
DNA Methylation
Enzyme Activation
Humans
Models, Molecular
Point Mutation
Substrate Specificity