Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex.
Andersen, Jacob Lauwring
Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex. [electronic resource] - Acta crystallographica. Section D, Biological crystallography Feb 2014 - 451-60 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1399-0047
10.1107/S1399004713030149 doi
Adaptor Proteins, Vesicular Transport--antagonists & inhibitors
Binding Sites
Coumarins--chemistry
Crystallization
Crystallography, X-Ray
HEK293 Cells
Humans
Leucine--analogs & derivatives
Ligands
Neurotensin--chemistry
Phenylalanine--chemistry
Recombinant Proteins--chemistry
Small Molecule Libraries--chemistry
Structure-Activity Relationship
Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex. [electronic resource] - Acta crystallographica. Section D, Biological crystallography Feb 2014 - 451-60 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1399-0047
10.1107/S1399004713030149 doi
Adaptor Proteins, Vesicular Transport--antagonists & inhibitors
Binding Sites
Coumarins--chemistry
Crystallization
Crystallography, X-Ray
HEK293 Cells
Humans
Leucine--analogs & derivatives
Ligands
Neurotensin--chemistry
Phenylalanine--chemistry
Recombinant Proteins--chemistry
Small Molecule Libraries--chemistry
Structure-Activity Relationship