IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone.

Chen, Yajun

IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone. [electronic resource] - American journal of physiology. Lung cellular and molecular physiology Apr 2014 - L797-807 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1522-1504

10.1152/ajplung.00347.2013 doi


Adenocarcinoma--drug therapy
Anti-Inflammatory Agents--pharmacology
Bronchi--drug effects
Cells, Cultured
Chromatin Immunoprecipitation
Cyclic AMP Response Element-Binding Protein--genetics
DNA-Directed RNA Polymerases--genetics
Dexamethasone--pharmacology
Electrophoretic Mobility Shift Assay
Gene Expression Regulation
Humans
Interleukin-1beta--pharmacology
Lung Neoplasms--drug therapy
Mucin 5AC--genetics
NF-kappa B--genetics
Promoter Regions, Genetic--genetics
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Receptors, Interleukin-1--genetics
Reverse Transcriptase Polymerase Chain Reaction