Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic β-cells while repressing α-cell functions.

Metzger, David E

Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic β-cells while repressing α-cell functions. [electronic resource] - Diabetes May 2014 - 1804-16 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1939-327X

10.2337/db13-0867 doi


Animals
Cell Differentiation
Co-Repressor Proteins--genetics
Gene Expression Regulation, Developmental
Glucagon--metabolism
Glucagon-Secreting Cells--metabolism
Homeodomain Proteins--genetics
Humans
Insulin-Secreting Cells--metabolism
Mice
Transcription Factors--genetics