Exogenous activation of LKB1/AMPK signaling induces G₁ arrest in cells with endogenous LKB1 expression.

Liang, Xiaoyan

Exogenous activation of LKB1/AMPK signaling induces G₁ arrest in cells with endogenous LKB1 expression. [electronic resource] - Molecular medicine reports Mar 2014 - 1019-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1791-3004

10.3892/mmr.2014.1916 doi


AMP-Activated Protein Kinase Kinases
AMP-Activated Protein Kinases--metabolism
Cyclin D1--metabolism
Cyclin D3--metabolism
Cyclin-Dependent Kinase Inhibitor p16--metabolism
Cyclin-Dependent Kinase Inhibitor p27--metabolism
Down-Regulation
G1 Phase Cell Cycle Checkpoints--physiology
Gene Expression Regulation, Enzymologic
Genetic Vectors--metabolism
HEK293 Cells
Hep G2 Cells
Human Umbilical Vein Endothelial Cells
Humans
Phosphorylation
Protein Serine-Threonine Kinases--genetics
Retinoblastoma Protein--metabolism
Signal Transduction
Tumor Suppressor Protein p53--metabolism
Up-Regulation