De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterization.

Brady, Ryan M

De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterization. [electronic resource] - Journal of medicinal chemistry Feb 2014 - 1323-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm401948b doi


Crystallography, X-Ray
Drug Design
Magnetic Resonance Spectroscopy
Molecular Mimicry
Molecular Structure
Spectrometry, Mass, Electrospray Ionization
Structure-Activity Relationship
Urea--analogs & derivatives
bcl-X Protein--antagonists & inhibitors