The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation.

Lesiak, Adam

The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Jan 2014 - 717-25 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.2884-13.2014 doi


Animals
Cells, Cultured
Coculture Techniques
Environmental Pollutants--toxicity
Excitatory Postsynaptic Potentials--drug effects
Female
Hippocampus--drug effects
Male
MicroRNAs--biosynthesis
Neurogenesis--drug effects
Organ Culture Techniques
Polychlorinated Biphenyls--toxicity
Rats
Rats, Sprague-Dawley
Ryanodine Receptor Calcium Release Channel--physiology
Spine--drug effects
Synapses--drug effects