The novel pyrrolo-1,5-benzoxazepine, PBOX-6, synergistically enhances the apoptotic effects of carboplatin in drug sensitive and multidrug resistant neuroblastoma cells.

Lennon, Jennifer C

The novel pyrrolo-1,5-benzoxazepine, PBOX-6, synergistically enhances the apoptotic effects of carboplatin in drug sensitive and multidrug resistant neuroblastoma cells. [electronic resource] - Biochemical pharmacology Feb 2014 - 611-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-2968

10.1016/j.bcp.2013.12.017 doi


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Carboplatin--pharmacology
Cell Line, Tumor
Drug Resistance, Multiple--drug effects
Drug Resistance, Neoplasm--drug effects
Drug Synergism
Humans
Neuroblastoma--drug therapy
Oxazepines--pharmacology
Pyrroles--pharmacology
Up-Regulation--drug effects