Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels.

Guillaumet-Adkins, Amy

Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels. [electronic resource] - Journal of hematology & oncology Jan 2014 - 4 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1756-8722

10.1186/1756-8722-7-4 doi


Acute Disease
Adolescent
Adult
Aged
Aged, 80 and over
Alternative Splicing
Biomarkers, Tumor--genetics
Child
Child, Preschool
CpG Islands--genetics
DNA Methylation
Female
Gene Expression Regulation, Neoplastic
HL-60 Cells
Hematologic Neoplasms--genetics
Humans
K562 Cells
Leukemia, Myeloid--genetics
Male
Middle Aged
Promoter Regions, Genetic--genetics
Reverse Transcriptase Polymerase Chain Reaction
U937 Cells
WT1 Proteins--genetics
Young Adult