Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis.

Lu, Ning

Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Feb 2014 - 1013-23 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.1300133 doi


Adolescent
Adult
Aged
Animals
Cell Line
Colitis--chemically induced
Colitis, Ulcerative--metabolism
Colon--immunology
Cyclooxygenase 2--biosynthesis
Cytokines--biosynthesis
Dextran Sulfate--toxicity
ErbB Receptors--deficiency
Female
Gene Expression Regulation--immunology
Humans
Immunity, Innate
Inflammation
Interferon-gamma--pharmacology
Interleukin-10--antagonists & inhibitors
Lipopolysaccharides--pharmacology
Macrophage Activation
Macrophages--immunology
Male
Mice
Mice, Inbred C57BL
Middle Aged
Myeloid Cells--metabolism
NF-kappa B--metabolism
Neutrophils--metabolism
Quinazolines--pharmacology
Regeneration
Signal Transduction--immunology
Spleen--immunology
Tumor Necrosis Factor-alpha--biosynthesis
Tyrphostins--pharmacology
Young Adult